Jobs at GondolaBio

A translational scientist who bridges discovery and early clinical development, designing and implementing biomarker and pharmacodynamic (PD) strategies that inform decision-making in IND-enabling and Phase 1/2 studies. Hands-on and execution-focused, with a track record of turning preclinical hypotheses into fit-for-purpose assays that perform in the clinic. Scientifically rigorous and detail-oriented, with a strong foundation in biochemistry and assay development. A collaborative, pragmatic communicator who partners across discovery, development, and external teams to deliver high-quality, decision-ready data, and who can clearly articulate experimental rationale, assay performance, and clinical relevance.

• Lead translational biomarker strategy for IND-enabling and Phase 1/2 programs, translating preclinical hypotheses into clinical assay plans with a focus on target engagement and PD.
• Direct the design, development, qualification/validation, and implementation of assays that support clinical endpoints and mechanistic understanding, ensuring scientific rigor, feasibility, and regulatory alignment.
• Oversee assay-related activities conducted by CROs, including protocol review, data quality assessment, and troubleshooting.
• Author and review regulatory documents supporting clinical development.

Preferred Education & Experience (Qualifications)

• PhD or MS in translational sciences, pharmacology biochemistry, bioanalytical science, or a related discipline.
• 8+ years of relevant industry or translational research experience.
• Hands-on experience developing or implementing biomarker strategy and assays supporting IND submission and Phase 1/2 programs.
• Working knowledge of bioanalytical principles, biomarker assay validation guidelines, and clinical sample workflows.
• Demonstrated ability to manage external partners and communicate effectively in cross-functional environments.

Nice-to-Haves

• Experience working in a biotech or fast-paced clinical development environment.
• Enzymology experience, such as enzyme kinetics, mechanism-of-action characterization, or development of enzyme activity assays to measure target engagement and PD.
• Expertise with multiple assay formats (e.g., ligand-binding, molecular, cell-based, and enzymatic activity assays).
• Experience contributing to regulatory submissions involving nonclinical pharmacology, biomarker, or assay component.

No matter your role at GondolaBio, successful team members are:

• Patient Champions, who put patients first and uphold strict ethical standards.
• Entrepreneurial Operators, who drive toward practical solutions and have an ownership mindset.
• Truth Seekers, who are detailed, rational, and humble problem solvers.
• Individuals Who Inspire Excellence in themselves and those around them.
• High-quality executors, who execute against goals and milestones with quality, precision, and speed.