Jobs at Cogent Biosciences

This position works in Drug Discovery to provide bioanalytical support for PK, PK/PD, TK, and TGI experiments across multiple programs. The successful candidate will utilize their strong knowledge of LC-MS/MS bioanalysis to quantitate small molecule drugs in biological matrices (plasma primarily). Independent method development, routine bioanalysis, and communication of high-quality data are hallmarks for the position. Maintenance, troubleshooting, and repair of LC-MS/MS instrumentation and software is expected. Secondary roles of the position include providing technical writing support and review as needed.

• Develop LC-MS/MS methods to quantitate small molecules in biological matrices
• Routine bioanalysis and data release to DMPK project leads
• Maintain, troubleshoot, and repair LC-MS/MS instrumentation and software, including coordination with service engineers for complex matters
• Support technical writing efforts and data QC for preclinical ADME IND efforts
• Good written and oral communication, including timely electronic laboratory notebook entry
• Proven work ethic, competence, enthusiasm, independence, and team focus

• Minimum of BA/BS with 10 years or MS with 8 years of analytical work in Pharma/Biotech
• LC-MS/MS
• Independence, awareness, and multi-tasking in a fast-paced environment
• Scientific and technical knowledge around small molecule quantitative bioanalysis
• Strong knowledge of LC-MS/MS instrumentation, troubleshooting, method development, and quantitation
• Microsoft Office Suite

Preferred Qualifications:

• Sciex QQQ or Shimadzu UPLC
• Knowledge of DMPK and relationships of in vitro and in vivo assays
• Non-compartmental PK modeling
• Report writing
• Process automation via software, robotics, or liquid handling